Q&A: Can Collagen Peptides be taken with GI Supplements, Probiotics, Vitamins?


May 24, 2021


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Can collagen peptides be taken with GI supplements, probiotics, and other vitamins? GI supplements will be trickier than probiotics and vitamins. Dr. Cate, M.D. and Charlie team up and make sense of it all in this customer Q&A.


Can collagen peptides be taken with GI supplements, probiotics, and other vitamins? Is there anything it shouldn’t be mixed with?Frances

There are a couple points to address in Frances’ question, so we’ll break each point out and address individually below.

Can collagen peptides be taken with GI supplements?

Dr. Cate’s answer:

If your gastrointestinal supplements contain enzymes, they may chop up some of the bioactive peptides. Unlike our normal digestive enzymes, which are not released until passing through the stomach, external enzymes can start breaking the stuff down if they’re mixed together or swallowed together.

Other than that, feel free to consume together.

Can collagen peptides be taken with probiotics & vitamins?

Dr. Cate’s answer:

There’s no reason to expect that probiotics and vitamins would interfere with collagen’s health effects or that collagen would interfere with the health effects of vitamins and probiotics.


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Collagen WITH vitamins and minerals? Sounds like the utopia of collagen + nutrition! Or is it? Could it be just fancy marketing? Thanks to Dr. Cate, M.D., we get to the bottom of this nutrition debate.

Is there anything collagen peptides shouldn’t be mixed with?

Charlie’s answer:

Soda! Never, ever, with soda. 🙂 See our collagen recipes for ideas.

Dr. Cate’s answer:

Vegetable oil! Never, ever, with vegetable oil. 🙂 (see: List of Good Fats and Oils versus Bad)

More helpful resources

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This Collagen College™ article created by:



Dr. Cate

Dr. Cate Shanahan is our Medical & Scientific Advisor. She is a Board-certified Family Physician, biochemist trained at Cornell University, and New York Times Bestseller.


Charlie Bailes - Founder CB Supplements

Charlie Bailes

If you've bought our multi collagen, there's a pretty darn good chance you've received an awesome personalized thank you note from Charlie. Aside from caring A LOT about customer appreciation, he's also our Founder and CEO and responsible for assembling our great team and vision.

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